Why Inflammation Is More Common In Women & What To Do

The sentence "Men are from Mars, women are from Venus" was first used to describe relationship conflict between the two sexes based on differences in DNA. But these genetic differences go well beyond compatibility and seep into health, too.

For example, women are more likely to deal with depression and anxiety1 than men, which may be caused in part by inflammation—something else that seems to impact women more than men.

"A woman's immune system is very reactive to changes in estrogen, progesterone, and testosterone, all of which influence immune activation and inflammation," says Jeffrey Bland, Ph.D., president and founder of Big Bold Health. He explains that this is because women's immune systems must be capable of supporting new life during pregnancy.

There are two types of inflammation: acute and chronic. Acute inflammation happens as a response to sudden damage in the body. This can range from a headache, sore throat, ingrown toenails, or an upset stomach. Chronic inflammation happens when your body sends inflammatory cells out to the body, but there is no damage to triage. This can result in autoimmune diseases like psoriasis, rheumatoid arthritis, asthma, chronic fatigue, and gastrointestinal conditions like irritable bowel syndrome (IBS).

Food has a powerful impact on the body's inflammatory pathways, Bland says—particularly for women.

"The Mediterranean Diet has been shown to have an anti-inflammatory effect in women due to the high levels of hormone- and immune-balancing nutrients," says Bland. This is a diet built around fruits, vegetables, whole grains, fish (particularly ones high in omega-3 fatty acids), extra-virgin olive oil, beans, and nuts. These foods are packed with phytochemicals—active compounds found in plants that help your immune system have an appropriate response to toxins, infection, injury, and other causes of inflammation.

To reduce chronic inflammation, he recommends women opt for a Meditteranean-style eating pattern and steer clear of foods such as fried foods, sugary foods, ultra-processed foods, and low-fiber foods.